[PDF][PDF] Multiple roles of 25-hydroxycholesterol in lipid metabolism, antivirus process, inflammatory response, and cell survival

Q Cao, Z Liu, Y Xiong, Z Zhong… - … Medicine and Cellular …, 2020 - downloads.hindawi.com
… , the role of 25-hydroxycholesterol (25-HC) in cholesterol and bile acid metabolism, antivirus
process, and inflammatory response … This review is aimed at revealing these functions and …

The role of cholesterol 25-hydroxylase in viral infections: Mechanisms and implications

P Yousefi, A Gholami, M Mehrjo, MH Razizadeh… - … -Research and Practice, 2023 - Elsevier
… activity of 25-hydroxycholesterol (25HC) against two oncogenic … influencing host lipid
metabolism and immune responses. The … viral pathogens and host lipid pathways. Harnessing the …

Studies in the antiviral molecular mechanisms of 25-hydroxycholesterol: Disturbing cholesterol homeostasis and post-translational modification of proteins

S Mao, J Ren, Y Xu, J Lin, C Pan, Y Meng… - European Journal of …, 2022 - Elsevier
multi-function viral inhibition of 25HC, in particular the ability to restrict viral fusion by affecting
intracellular lipid metabolism, … Multiple antiviral molecular mechanisms of 25HC in humans …

Pathogenic role of 25-hydroxycholesterol in cancer development and progression

SS Ejam, RO Saleh, MJ Catalan Opulencia… - Future …, 2022 - Future Medicine
… would significantly impact fatty acid metabolism. Johnson et al… significant role in the
inflammatory response, innate immune … 10 μg/ml did not influence cell survival or frequency of …

Research progress on the mechanism of cholesterol-25-hydroxylase in intestinal immunity

G Zhong, C He, S Wang, C Lin, M Li - Frontiers in Immunology, 2023 - frontiersin.org
… the oxidation of cholesterol into 25-hydroxycholesterol (25-HC)… of regulating lipid metabolism
and immune cell function via … for macrophage survival and the innate immune response. …

[HTML][HTML] Cholesterol 25-hydroxylase suppresses avian reovirus replication by its enzymatic product 25-hydroxycholesterol

Y Wang, W Zuo, Y Zhang, Z Bo, C Zhang… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
functions to regulate cholesterol homeostasis, antivirus … The viability of DF-1 cells after 25HC
treatment was … insights into the role of lipids in the innate immune response to ARV infection…

Serum 25-hydroxycholesterol levels are increased in patients with coronavirus disease 2019

T Asano, T Wakabayashi, Y Kondo, K Okada… - Journal of Clinical …, 2023 - Elsevier
… , including infection and inflammation. Particularly, 25-hydroxycholesterol (25HC) inhibits
the replication of various viral pathogens.3, 4, 5 Recently, SARS-CoV-2 infection has been …

25-Hydroxycholesterol mitigates hepatic ischemia reperfusion injury via mediating mitophagy

Q Cao, J Luo, Y Xiong, Z Liu, Q Ye - International Immunopharmacology, 2021 - Elsevier
… (25HC) is a kind of oxysterol involved in inflammatory and immune responses. However,
its function … and pathological process, such as cholesterol and bile acid metabolism, anti-viral …

25-Hydroxycholesterol-3-sulfate attenuates inflammatory response via PPARγ signaling in human THP-1 macrophages

L Xu, S Shen, Y Ma, JK Kim… - … and Metabolism, 2012 - journals.physiology.org
lipid metabolism. In this paper, we report the effect of 25HC3S and its precursor 25-hydroxycholesterol
(… ) play major roles in the regulation of lipid metabolism, glucose homeostasis, and …

Cholesterol 25-Hydroxylase inhibits bovine parainfluenza virus type 3 replication through enzyme activity-dependent and-independent ways

L Lv, G Zhao, H Wang, H He - Veterinary microbiology, 2019 - Elsevier
… of cholesterol to production of 25-hydroxycholesterol (25HC) and … Cell viability then was
determined by an MTT assay … which regulates cholesterol and lipid metabolism. Recent studies …